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After 24 h, cells were infected with icSARS-CoV-2-mNG at a MOI = 0.5 or with SARS-CoV-2 Omicron at a MOI = 1.1

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Steinberg) Increasing brain activity can lead to the release of trophic factors, axonal sprouting, and myelinationall of which are beneficial for brain repair [76, 77]

Natural compounds evaluated in these models have demonstrated promising results across key pathological pathways, including, reduction of oxidative stress, inhibition of AChE, modulation of inflammatory pathways, preservation of blood-brain barrier integrity, enhancement of spatial and memory-related behaviors

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